i also go an optical mouse, which i love. it takes that much > less pressure to > move the thing. and one of those mousepads with the gel pack > wrist rest. I'd recommend a trackball so only your thumb moves, and minute distances at that. (logitech marble is my fave) Get an adjustable height desk and an adjustable height chair, adjust them so that with feet comfortable on the floor your arms can rest comfortably on the desk, site the trackball mouse so that your arm and wrist are supported while using. Keep an eye on the clock and do the cubicle dance every hour or so. Don't keep everything close to hand, deliberately locate some of the things you use regularly so that you have to get up and get them. Time compresses when you're using a computer - what seems like half an hour surfing the net was probably two or three hours. good luck.